Wegovy is a once-weekly injectable drug accepted for weight reduction and weight administration.
What’s Wegovy?
Wegovy, accepted by the FDA in June 2021, is a model title for semaglutide, a drug additionally present in Ozempic.
As a GLP-1 receptor agonist, Wegovy mimics a pure hormone that suppresses urge for food and slows digestion, serving to with weight administration.
It’s administered by way of a once-weekly injection utilizing a dose that steadily will increase to a upkeep degree over 17 weeks.
Will my physician prescribe Wegovy for weight reduction?
Wegovy is FDA-approved particularly to assist with weight reduction in people who find themselves overweight or obese with no less than one weight-related situation equivalent to hypertension (hypertension), sleep apnea, or sure coronary heart circumstances.
Usually, a body-mass index (BMI, a measure of weight relative to peak) of 30 or extra qualifies somebody for a prescription, although a BMI of 27 could also be adequate if weight-related well being points are current.
Whereas some docs might prescribe Wegovy off-label (in a fashion not formally accepted by the FDA) to those that don’t meet these standards, it’s typically reserved for individuals who haven’t achieved vital weight reduction by food plan and train alone.
Word that Wegovy ought to be used along with a reduced-calorie food plan and elevated bodily exercise.
How a lot weight do folks lose on Wegovy?
Wegovy has been proven to considerably assist with weight reduction by suppressing urge for food and slowing digestion, permitting folks to eat much less with out feeling disadvantaged. Moreover, it reduces the quantity of glucose the liver releases, bettering metabolic well being. These results collectively contribute to weight reduction.
In scientific trials, 85 p.c of individuals misplaced no less than 5 p.c of their physique weight, a charge of effectiveness that surpasses many different traditionally obtainable medication.
Within the STEP 4 trial, about 40 p.c of individuals misplaced greater than 20 p.c of their physique weight, with the most typical loss being 10.6 p.c of their pre-trial weight. The extent of weight reduction additionally depends upon the period of remedy use.
How rapidly do you see weight reduction?
Weight reduction varies by particular person and requires time, with most research monitoring progress as much as 68 weeks.
Scientific trials point out that weight reduction sometimes plateaus round 52 weeks.
Preliminary outcomes may be noticeable sooner, with many individuals shedding about 6 p.c of their beginning physique weight throughout the first 12 weeks when sticking to prescribed food plan and train plans. By one yr, the typical weight reduction reported was practically 16 p.c.
Whereas instant results can happen, sustaining weight reduction is a long-term dedication.
Communicate together with your healthcare supplier to know what to anticipate based mostly in your well being profile and the way lengthy it would take to see vital outcomes.
How a lot Wegovy do it is advisable take for weight reduction?
Scientific trials have proven that the utmost weekly dose of Wegovy — 2.4 milligrams (mg) of semaglutide — ends in vital weight reduction, with individuals seeing a mean discount of practically 15 p.c in physique weight, in comparison with 2.4 p.c with a placebo (inactive remedy).
This dosage is reached steadily over 17 weeks, following a routine that builds as much as the complete dose. Decrease doses have additionally been proven to be efficient however much less so than the two.4 mg dose.
If you happen to can’t tolerate the utmost dose resulting from unintended effects like nausea or digestive points, your supplier may regulate the dosage briefly. Discontinuation of Wegovy is really helpful if the complete dose stays constantly insupportable.
How lengthy do you are taking Wegovy for weight reduction?
Wegovy is usually prescribed as a long-term weight-loss remedy.
The period of remedy can differ relying in your well being targets, the effectiveness of the remedy, and your capability to tolerate it.
For a lot of, Wegovy is a part of an ongoing routine that will proceed for so long as the remedy helps with weight reduction and administration with out inflicting unacceptable unintended effects.
At all times seek the advice of together with your healthcare supplier to find out the suitable period of Wegovy remedy in your well being wants and to make changes as your well being improves or if problems come up.
Will I acquire the load again if I cease taking Wegovy?
Whereas some weight reduction achieved with Wegovy could also be long-lasting, most individuals are inclined to regain a good portion of the load after discontinuing the remedy.
Analysis signifies that inside one yr of stopping Wegovy, most customers regain about two-thirds of the load they’d misplaced.
To maximise the effectiveness of Wegovy and maintain weight reduction, it is very important mix the remedy with ongoing dietary adjustments and elevated bodily exercise.
Seek the advice of your healthcare supplier for steerage on managing weight earlier than, throughout, and after remedy.
If the remedy isn’t working nicely for you, different FDA-approved weight-loss medication equivalent to Saxenda and Zepbound could also be choices.
Be taught extra in: Zepbound vs. Wegovy: How Do They Evaluate?
What’s the largest dose for weight reduction?
The utmost really helpful weekly dose of Wegovy is 2.4 milligrams, sometimes delivered utilizing a pen with a darkish grey label.
This dose has been recognized in scientific trials as the best for attaining vital weight reduction, with the typical individual shedding greater than 10 p.c of their beginning weight.
Whereas some docs might prescribe doses increased than 2.4 mg for off-label makes use of, this will result in extra pronounced unintended effects. Subsequently, 2.4 mg per week is the usual most dose for weight reduction as accepted by the FDA.
Learn extra in: Wegovy Dosage Information: How A lot Ought to You Take?
What’s the greatest time to take Wegovy?
There isn’t a particular greatest time of day to take Wegovy per scientific research. The hot button is consistency in scheduling: select in the future of the week to manage the injection and keep on with the identical day every week.
You’ll be able to take it at any time in your chosen day.
To assist keep in mind your dosing schedule, think about marking it on a calendar or setting cellphone reminders. This helps make sure that you don’t miss a dose.
What are the unintended effects of Wegovy?
Frequent unintended effects embody nausea, vomiting, diarrhea, abdomen ache, constipation, heartburn, fuel, bloating, and tiredness.
Hypoglycemia (low blood sugar) may happen, particularly in these taking insulin. Signs to look at for embody dizziness, confusion, temper adjustments, shakiness, and a quick heartbeat.
Extra severe however uncommon unintended effects embody thyroid tumors, pancreatitis, imaginative and prescient adjustments, kidney issues, psychological adjustments, and extreme allergic reactions.
Seek the advice of your physician for an entire understanding of the dangers and advantages of Wegovy.
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