Trulicity is a once-weekly injectable remedy that helps handle blood glucose (sugar) ranges, enhance A1c (a measure of glucose management over the earlier 2 to three months), and even help weight reduction.
This text covers all the pieces you have to learn about Trulicity dosing.
What dose do you usually begin with?
When beginning Trulicity, your physician will possible start with a low dose, usually 0.75 mg as soon as weekly, to assist your physique regulate and reduce negative effects. The drugs might be taken with or with out meals.
Widespread negative effects embody nausea, vomiting, diarrhea, fatigue, and suppressed urge for food, which may vary from gentle to extreme.
If after 4 weeks you want extra blood sugar administration and tolerate the remedy nicely, your physician might improve your dose to 1.5 mg as soon as weekly.
What’s a standard Trulicity dose?
There isn’t a “regular” dose, because it varies by the individual, however there’s a customary “upkeep” dose.
This dose is established after your physique has adjusted to the remedy, permitting you to gauge its effectiveness for blood sugar administration and the severity of any negative effects.
Most adults begin with 0.75 mg as soon as weekly and, after 4 weeks, improve to a upkeep dose of 1.5 mg. For kids ages 10 and up with sort 2 diabetes, the beginning and most upkeep dose is 0.75 mg and 1.5 mg as soon as weekly, respectively.
How and when are you able to improve your dose?
Dose will increase ought to solely be accomplished underneath your physician’s steerage. You’ll usually stay on the introductory dose of 0.75 mg for the primary 4 weeks to watch negative effects and therapy response.
If further blood sugar administration is required, your physician might improve your dose to 1.5 mg.
After one other 4 weeks, if additional administration is required and negative effects are minimal, your dose could also be elevated to three mg, and finally to a most of 4.5 mg weekly for adults. The utmost dose for youngsters stays 1.5 mg.
Typical dosing schedule chart
So for adults, a typical Trulicity dosing schedule would possibly appear to be the next:
| Month | Dosage | Frequency | Notes |
| Month 1 | 0.75 mg | As soon as weekly for 4 weeks | Beginning dose |
| Month 2 | 1.5 mg | As soon as weekly for 4 weeks | Improve if wanted (elective) |
| Month 3 | 3 mg | As soon as weekly for 4 weeks | Improve if wanted (elective) |
| Month 4 and past | 4.5 mg | As soon as weekly | Most dose (elective) |
What’s the appropriate dose for me?
Discovering the correct dose takes time, endurance, and presumably some trial and error. It is dependent upon your well being historical past, targets, way of life, and the way nicely you tolerate negative effects.
Usually, increased doses of GLP-1 agonists like Trulicity can result in higher outcomes, equivalent to decrease blood sugar ranges, weight reduction, and improved A1c, however in addition they improve the chance of negative effects.
All the time regulate your dose underneath your healthcare supplier’s steerage.
What’s the appropriate dose for weight reduction?
Whereas Trulicity isn’t FDA-approved for weight reduction, many customers report reducing weight whereas taking it. Because it’s not particularly accepted for this function, there isn’t an official dose really helpful for weight reduction.
Trulicity works greatest for weight administration when mixed with wholesome consuming and elevated bodily exercise.
For those who’re contemplating remedy for weight reduction, seek the advice of your physician about FDA-approved choices. Word that you could’t take two GLP-1 agonists concurrently, like Trulicity and Wegovy or Zepbound.
Different drugs, like metformin, might be taken alongside Trulicity to assist with weight reduction.
Be taught extra in: Trulicity and Weight Loss: Can Trulicity Assist You Lose Weight?
What occurs if I cease taking Trulicity?
By no means cease taking your diabetes drugs with out consulting your healthcare supplier.
Abruptly stopping Trulicity can result in adversarial results equivalent to elevated starvation, fatigue, weight achieve, increased insulin resistance, decreased insulin sensitivity, and elevated blood sugar ranges.
For those who expertise extreme negative effects, your insurance coverage not covers Trulicity, or it not suits your way of life, converse along with your supplier about different remedies.
Are there completely different Trulicity pens?
Sure, Trulicity is available in 4 single-dose pens based mostly in your prescribed dose. For a month’s prescription, you’ll obtain 4 pens, out there within the following doses:
- 0.75 mg
- 1.5 mg
- 3 mg
- 4.5 mg
Single-dose pens guarantee you possibly can’t unintentionally over-inject except taken greater than as soon as every week. Nevertheless, in addition they imply there’s no additional remedy if a pen is broken or misplaced.
What’s the strongest Trulicity?
All Trulicity pens include the identical lively ingredient, dulaglutide, and the bigger dosing pens don’t have a stronger formulation — only a increased dose per week.
Growing your dose means you’re taking extra of the remedy weekly, not a stronger model.
All the time observe your physician’s prescribed dose and by no means take greater than directed.
What’s the most weekly dose?
The very best dose of Trulicity you possibly can take every week is 4.5 mg.
You may regulate your dosing day or time so long as it’s been at the very least 72 hours since your final dose. If it’s been lower than 72 hours since your final dose, wait till the next week to choose a brand new dosing day.
By no means take two doses inside three days of one another, as this could improve the chance of extreme negative effects like nausea, vomiting, and dangerously low blood sugar (hypoglycemia).
Signs of extraordinarily low blood sugar embody dizziness, confusion, speedy coronary heart fee, shallow respiratory, shakiness, grogginess, fatigue, and unconsciousness. Search emergency medical consideration if you happen to suspect an overdose.
What do I do if I miss a dose?
Don’t fear — lacking one weekly dose gained’t instantly elevate your blood sugar or trigger weight achieve.
For those who miss a dose and there are at the very least 3 days till your subsequent scheduled dose, you possibly can take the missed dose with out considerably altering your schedule.
If it’s been greater than 3 days, skip the missed dose and proceed along with your subsequent dose as scheduled. By no means take two doses inside a 72-hour interval. That will help you bear in mind, set an alarm or reminder in your cellphone to your weekly dose.
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