Trulicity and Ozempic are each once-weekly GLP-1 agonist injections used to decrease blood sugar ranges in individuals with kind 2 diabetes.
This text will discover the important thing similarities and variations that will help you decide which treatment is perhaps best for you.
What are Trulicity and Ozempic?
Trulicity and Ozempic are name-brand injectable medicine labeled as GLP-1 agonists. Each are permitted by the U.S. Meals and Drug Administration (FDA) to handle blood sugar ranges in individuals with kind 2 diabetes.
Trulicity is permitted for kids ages 10 and up and adults, whereas Ozempic is permitted for adults solely.
Each medicines may assist with weight reduction and assist forestall stroke, coronary heart assault, and untimely demise in these with kind 2 diabetes and preexisting coronary heart illness.
Learn extra in: All the things You Have to Know About Trulicity and All the things You Have to Know About Ozempic.
Why would you are taking Trulicity or Ozempic?
You could be prescribed considered one of these medicines in case you have kind 2 diabetes, notably if you’re coping with insulin resistance, persistent excessive blood sugar (particularly after meals), and issue sustaining a wholesome weight.
Research point out that GLP-1 agonists like Ozempic and Trulicity can promote weight reduction, though neither is FDA-approved for this function.
If prescribed off-label (in a way not formally permitted by the FDA), these medicines may additionally be used to enhance insulin sensitivity and assist with weight reduction, even in these with out kind 2 diabetes. All the time take them beneath a health care provider’s steering.
See extra in: All the things You Have to Know About Trulicity and All the things You Have to Know About Ozempic.
How are Trulicity and Ozempic comparable?
Trulicity and Ozempic share a number of similarities:
They don’t exchange insulin
These medicines don’t exchange insulin however can complement it in managing blood sugar ranges over time.
They assist decrease blood sugar step by step with out inflicting acute hypoglycemia (low blood sugar).
As insulin resistance decreases, chances are you’ll require much less insulin to handle your blood sugar ranges.
They’re injectable medicines, taken as soon as every week
Each can be found solely as subcutaneous (beneath the pores and skin) injections, taken as soon as every week.
It’s vital to keep up consistency by administering the remedy on the identical day and on the similar time every week.
They’ve comparable unwanted side effects
Trulicity and Ozempic share many unwanted side effects, which can embody:
- Nausea
- Vomiting
- Diarrhea
- Stomachache
- Suppressed urge for food
- Weight reduction
- Constipation
- Fatigue
- Low blood sugar (if used with insulin)
Each medicines, although not often, can improve the chance of creating medullary thyroid carcinoma (MTC). When you’ve got a private or household historical past of MTC, you must keep away from these medicines.
Moreover, the FDA has issued a black field warning for each medicine concerning their affiliation with an elevated danger of thyroid most cancers.
Learn extra in: Trulicity Aspect Results: What You Have to Know and Ozempic Aspect Results: What You Have to Know.
They trigger weight reduction and decrease blood sugar ranges
Each Trulicity and Ozempic successfully decrease blood sugar ranges and promote weight reduction.
Though not FDA-approved particularly for weight reduction, many individuals expertise a discount of greater than 5 p.c of their physique weight whereas taking these medicines.
Since they aren’t permitted for weight reduction, there isn’t a really helpful dosage particularly for that function.
Should you’re contemplating choices for managing your weight, Trulicity or Ozempic is perhaps appropriate selections to debate along with your healthcare supplier.
Learn extra in: Trulicity and Weight Loss: Can Trulicity Assist You Lose Weight? and Can Ozempic Assist You Lose Weight?
They are often taken with or with out meals
The medicines could be taken with or with out meals, in contrast to insulin, which might trigger sudden drops in blood sugar.
The most effective time to take your dose is whenever you’re most definitely to recollect it every week.
See extra in: Trulicity Dosing: How A lot Ought to You Take? and Ozempic Dosage Information: How A lot Ought to You Take?
Whereas not required, having a small snack earlier than or after your injection could assist alleviate nausea.
Go for bland meals like bananas, rice, toast, applesauce, or clear-broth soups. Eating regimen performs an important position when adjusting to a brand new treatment, so be aware of the meals you select.
See extra in: Meals to Keep away from When Taking Trulicity and Meals to Keep away from Whereas Taking Ozempic.
How are Trulicity and Ozempic totally different?
Though comparable, the medicines have key variations.
Their energetic components are totally different
Though Trulicity and Ozempic are each GLP-1 agonists, they differ of their energetic components. Trulicity comprises dulaglutide, whereas Ozempic comprises semaglutide.
If you’re allergic to both of those components, seek the advice of your physician earlier than beginning remedy, as you would expertise extreme unwanted side effects.
Ozempic could also be more practical
In a pivotal examine evaluating semaglutide (Ozempic) and dulaglutide (Trulicity) in individuals with kind 2 diabetes, semaglutide was discovered to be more practical at bettering blood sugar administration and decreasing physique weight at each excessive and low doses, with the same security profile.
Should you’re coping with extreme insulin resistance and issue sustaining a wholesome weight, think about discussing Ozempic along with your physician to see if it is perhaps a superb match for you.
Incessantly requested questions
Can I change between the 2?
Sure, it’s potential to change between Trulicity and Ozempic.
Nevertheless, your healthcare supplier will seemingly advocate ready every week after your final dose of 1 earlier than beginning the opposite to attenuate the chance of extreme unwanted side effects.
Should you’re allergic to both of their energetic components — semaglutide in Ozempic or dulaglutide in Trulicity — you shouldn’t change between them.
Should you’re experiencing vital unwanted side effects with one, attempting the opposite is perhaps a greater choice, as your physique could tolerate it otherwise.
Can I take each on the similar time?
No, you can not take Trulicity and Ozempic collectively, despite the fact that they’ve totally different energetic components.
Double-dosing GLP-1 agonists can result in extreme unwanted side effects, together with dangerously low blood sugar, which might be life-threatening if not handled.
Should you by chance take each medicines on the similar time or inside a 2-day interval, name your physician instantly or search emergency medical consideration.
Which treatment is correct for me?
Selecting between Trulicity and Ozempic is a call that you simply and your healthcare supplier ought to make collectively, primarily based in your well being historical past, objectives, life-style, and preferences.
All the time think about the energetic components and any potential allergic reactions. Moreover, verify your medical insurance protection to see which medicines are on the popular drug record, making certain you choose an reasonably priced, long-term choice.
Whereas there are not any generic variations of Trulicity or Ozempic, your physician could recommend extra reasonably priced alternate options.
Study extra in All the things You Have to Know About Trulicity and All the things You Have to Know About Ozempic. Did you discover this text useful? Click on Sure or No beneath to tell us!
