Mounjaro benefits and side effects explained: All you need to know

Weight problems is a significant well being concern on this planet, as tens of millions of individuals have extreme fats deposits of their our bodies. In 2022, 890 million individuals had been discovered to be dwelling with weight problems, in accordance with the World Well being Group. So, it comes as no shock that pharmaceutical corporations and authorities businesses globally try to give you an answer. That has brough weight reduction medication into the image. Most of those prescribed medicines assist by mimicking the hormones that play a key function in regulating urge for food and starvation. Mounjaro is one such treatment, which is used to handle kind 2 diabetes and likewise has weight reduction advantages. Know all about the advantages and unwanted effects of Mounjara, a weekly injectable drug, earlier than utilizing it to drop a few pounds.

What’s Mounjaro?

Mounjaro is the model title for tirzepatide, a once-weekly injectable treatment accredited by the US Meals and Drug Administration for kind 2 diabetes. It’s also used off-label for weight reduction, which suggests it’s prescribed for a function apart from what it’s been accredited for.

“In contrast to earlier GLP-1 agonists like semaglutide, which is offered beneath totally different manufacturers, together with Ozempic, Mounjaro acts on two incretin hormones GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 (glucagon-like peptide-1),” says endocrinologist Dr Archana Juneja. This fashion, it enhances its efficacy for each glycemic management and weight reduction.

What are the advantages of Mounjaro?

Listed below are the important thing advantages of Mounjaro:

1. Manages diabetes

It helps in managing kind 2 diabetes by rising the manufacturing of insulin within the physique. This in flip helps in decreasing blood sugar, as the quantity of sugar your liver produces decreases. “It stimulates the pancreas to launch extra insulin in a glucose-dependent method, that means it primarily works when blood glucose ranges are excessive, decreasing the danger of hypoglycemia,” explains the professional.

2. Helps with weight reduction

Mounjaro has demonstrated vital weight discount in non-diabetics as properly. A brand new examine, introduced on the European Congress on Weight problems in Spain in Could 2025, discovered {that a} weekly dose of tirzepatide can result in vital and constant weight reduction for as much as 3 years in overweight or obese adults who should not diabetics. “This medication works on the mind’s hypothalamus, which controls starvation. It helps to suppress urge for food and decelerate gastric emptying, resulting in early satiety and aiding weight reduction,” says the professional.

Mounjaro doses

The doses enhance progressively, however ensure that to observe your physician’s recommendation.

• The advisable beginning dose is 2.5 mg, which must be injected beneath the pores and skin of your abdomen, thigh, or higher arm as soon as weekly, as per the FDA.
• 4 weeks later, the dose might be elevated to five mg.
• The utmost dosage is 15 mg, which ought to be injected subcutaneously as soon as weekly.

For those who miss a dose, a jab must be given as quickly as attainable inside 4 days after the missed dose.

Does Mounjaro trigger hair loss?

Hair loss just isn’t a recognized or frequent aspect impact of Mounjaro itself. Nevertheless, fast weight reduction, which is frequent with tirzepatide, can result in telogen effluvium, a short lived hair loss drawback. “This kind of hair loss is often reversible and never instantly tied to the load loss drug’s mechanism,” says Dr Juneja. For those who expertise hair loss whereas taking Mounjaro, you need to be checked for dietary deficiencies like iron, zinc, vitamin B12 and protein.

What are the unwanted effects of Mounjaro?

Listed below are a few of the unwanted effects of Mounjaro:

• Nausea: It’s a frequent aspect impact, skilled while you begin taking this weight reduction drug. “It’s usually because of the delayed gastric emptying attributable to the treatment, and often improves because the physique adjusts to the drug,” says the professional.
• Vomiting: It happens in some individuals, significantly if the dose is elevated too shortly. It’s the physique’s response to modifications in digestion and urge for food regulation.
• Diarrhea: Free or frequent stools may end up from modifications in intestine motility, which is the stretching of the muscle tissues within the gastrointestinal tract.
• Constipation: If not diarrhea, some individuals could expertise slowed bowel actions or have problem passing stool attributable to modifications in digestion.
• Indigestion: A sense of discomfort or burning within the higher stomach after consuming could also be felt whereas utilizing Mounjaro.
• Pancreatitis: Irritation of the pancreas is a uncommon, however severe aspect impact of this weight reduction drug. It could possibly result in extreme belly ache, nausea and vomiting.
• Hypoglycemia (low blood sugar): Mounjaro alone has a low danger of inflicting hypoglycemia. “Nevertheless, if utilized in mixture with insulin or sulfonylureas (anti-diabetic drugs), the danger will increase. Sweating, dizziness and confusion are a few of its signs,” says the professional.
• Liver toxicity: It’s uncommon, however hepatotoxicity, often known as liver toxicity, could also be related to tirzepatide use. Throughout a examine, revealed within the European Journal Of Case Studies In Inner Drugs, researchers discovered that liver toxicity was skilled after escalating doses of tirzepatide.